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Dolan, Mary Eileen
One or more keywords matched the following items that are connected to Dolan, Mary Eileen
Item TypeName
Concept Cell Line, Transformed
Concept Cell Line, Tumor
Concept Cell Line
Academic Article O6-alkylguanine-DNA alkyltransferase in cutaneous T-cell lymphoma: implications for treatment with alkylating agents.
Academic Article Role of glutathione and nucleotide excision repair in modulation of cisplatin activity with O6-benzylguanine.
Academic Article Characterization of multiple promoters in the human carboxylesterase 2 gene.
Academic Article Heritability and linkage analysis of sensitivity to cisplatin-induced cytotoxicity.
Academic Article Effect of population and gender on chemotherapeutic agent-induced cytotoxicity.
Academic Article Genetic variants contributing to daunorubicin-induced cytotoxicity.
Academic Article Role of copper transporters in resistance to platinating agents.
Academic Article Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity.
Academic Article Whole-genome approach implicates CD44 in cellular resistance to carboplatin.
Academic Article Identification of genetic variants and gene expression relationships associated with pharmacogenes in humans.
Academic Article Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines.
Academic Article Identification of genomic regions contributing to etoposide-induced cytotoxicity.
Academic Article Use of cell lines in the investigation of pharmacogenetic loci.
Academic Article Use of CEPH and non-CEPH lymphoblast cell lines in pharmacogenetic studies.
Academic Article Role of GADD34 in modulation of cisplatin cytotoxicity.
Academic Article Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.
Academic Article Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice.
Academic Article Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach.
Academic Article Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.
Academic Article Population differences in microRNA expression and biological implications.
Academic Article Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
Academic Article Enhancement of cisplatin [cis-diammine dichloroplatinum (II)] cytotoxicity by O6-benzylguanine involves endoplasmic reticulum stress.
Academic Article A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter.
Academic Article Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.
Academic Article Genetic architecture of transcript-level variation in humans.
Academic Article Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans.
Academic Article PACdb: a database for cell-based pharmacogenomics.
Academic Article Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation.
Academic Article Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.
Academic Article An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers.
Academic Article Regulatory polymorphisms in ß-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.
Academic Article Clinical translation of cell-based pharmacogenomic discovery.
Academic Article Copy number polymorphisms and anticancer pharmacogenomics.
Academic Article Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis.
Academic Article Population differences in the rate of proliferation of international HapMap cell lines.
Academic Article A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.
Academic Article Mapping genes that contribute to daunorubicin-induced cytotoxicity.
Academic Article Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
Academic Article Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
Academic Article Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.
Academic Article Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel.
Academic Article Effect of O6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts.
Academic Article Effect of O6-alkylguanine pretreatment on the sensitivity of human colon tumor cells to the cytotoxic effects of chloroethylating agents.
Academic Article Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
Academic Article Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
Academic Article Correlation between O6-methylguanine-DNA-methyltransferase activity and resistance of human cells to the cytotoxic and mutagenic effect of N-methyl-N'-nitro-N-nitrosoguanidine.
Academic Article Studies of the repair of O6-alkylguanine and O4-alkylthymine in DNA by alkyltransferases from mammalian cells and bacteria.
Academic Article Depletion of O6-methylguanine-DNA-methyltransferase in human fibroblasts increases the mutagenic response to N-methyl-N'-nitro-N-nitrosoguanidine.
Academic Article Somatic acquisition and signaling of TGFBR1*6A in cancer.
Academic Article Poly(ADP-ribose) polymerase inhibitor ABT-888 potentiates the cytotoxic activity of temozolomide in leukemia cells: influence of mismatch repair status and O6-methylguanine-DNA methyltransferase activity.
Academic Article Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
Academic Article Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.
Academic Article 1,3- vs 1,5-intramolecular alkylation reactions in isophosphoramide and phosphoramide mustards.
Academic Article Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia.
Academic Article Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.
Academic Article The kinase inhibitor O6-cyclohexylmethylguanine (NU2058) potentiates the cytotoxicity of cisplatin by mechanisms that are independent of its effect upon CDK2.
Academic Article MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.
Academic Article Lymphoblastoid cell lines in pharmacogenomics: how applicable are they to clinical outcomes?
Academic Article Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
Academic Article Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels.
Academic Article Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.
Academic Article Genetic and epigenetic variants contributing to clofarabine cytotoxicity.
Academic Article Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells.
Academic Article EPS8 inhibition increases cisplatin sensitivity in lung cancer cells.
Academic Article The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
Academic Article Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses.
Academic Article Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.
Academic Article RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients.
Academic Article Characterization of CpG sites that escape methylation on the inactive human X-chromosome.
Academic Article Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
Academic Article Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach.
Academic Article Integration of genetic and functional genomics data to uncover chemotherapeutic induced cytotoxicity.
Academic Article Identification of Novel Protein Expression Changes Following Cisplatin Treatment and Application to Combination Therapy.
Academic Article Gene and MicroRNA Perturbations of Cellular Response to Pemetrexed Implicate Biological Networks and Enable Imputation of Response in Lung Adenocarcinoma.
Academic Article Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms.
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